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Growth arrest signaling of the Raf/MEK/ERK pathway in cancer
The Raf/MEK/extracellular signal-regulated kinase (ERK) pathway has a pivotal role in facilitating cell proliferation, and its deregulated activation is a central signature of many epithelial cancers. However paradoxically, sustained activity of Raf/MEK/ERK can also result in growth arrest in many d...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079089/ https://ncbi.nlm.nih.gov/pubmed/24999356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-014-1299-x |
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