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Growth arrest signaling of the Raf/MEK/ERK pathway in cancer

The Raf/MEK/extracellular signal-regulated kinase (ERK) pathway has a pivotal role in facilitating cell proliferation, and its deregulated activation is a central signature of many epithelial cancers. However paradoxically, sustained activity of Raf/MEK/ERK can also result in growth arrest in many d...

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Bibliografski detalji
Glavni autor: Park, Jong-In
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079089/
https://ncbi.nlm.nih.gov/pubmed/24999356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11515-014-1299-x
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