Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro.
Raf-1 is a serine/threonine kinase which is essential in cell growth and differentiation. Tyrosine kinase oncogenes and receptors and p21ras can activate Raf-1, and recent studies have suggested that Raf-1 functions upstream of MEK (MAP/ERK kinase), which phosphorylates and activates ERK. To determi...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1993
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364724/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6615-6620.1993 |
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