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The deubiquitinating enzyme USP48 stabilizes TRAF2 and reduces E-cadherin-mediated adherens junctions
The tumor necrosis factor receptor–associated factor 2 (TRAF2) is a second messenger adaptor protein that plays an essential role in propagating TNF-α-mediated signaling pathways. Modulation of TRAF2 activity by ubiquitination is well studied; however, the deubiquitinating enzyme (DUB), which regula...
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| Publicado no: | FASEB J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5731130/ https://ncbi.nlm.nih.gov/pubmed/28874458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700415RR |
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