Flow Cytometric Detection of PrP(Sc) in Neurons and Glial Cells from Prion-Infected Mouse Brains

In prion diseases, an abnormal isoform of prion protein (PrP(Sc)) accumulates in neurons, astrocytes, and microglia in the brains of animals affected by prions. Detailed analyses of PrP(Sc)-positive neurons and glial cells are required to clarify their pathophysiological roles in the disease. Here,...

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Vydáno v:J Virol
Hlavní autoři: Yamasaki, Takeshi, Suzuki, Akio, Hasebe, Rie, Horiuchi, Motohiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Prions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730779/
https://ncbi.nlm.nih.gov/pubmed/29046463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01457-17
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