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Retrograde Transport by Clathrin-Coated Vesicles is Involved in Intracellular Transport of PrP(Sc) in Persistently Prion-Infected Cells

Intracellular dynamics of an abnormal isoform of prion protein (PrP(Sc)) are tightly associated with prion propagation. However, the machineries involved in the intracellular trafficking of PrP(Sc) are not fully understood. Our previous study suggested that PrP(Sc) in persistently prion-infected cel...

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Publicado en:Sci Rep
Main Authors: Yamasaki, Takeshi, Suzuki, Akio, Hasebe, Rie, Horiuchi, Motohiro
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095914/
https://ncbi.nlm.nih.gov/pubmed/30115966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30775-1
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