Comparison of abnormal isoform of prion protein in prion-infected cell lines and primary-cultured neurons by PrP(Sc)-specific immunostaining

We established abnormal isoform of prion protein (PrP(Sc))-specific double immunostaining using mAb 132, which recognizes aa 119–127 of the PrP molecule, and novel PrP(Sc)-specific mAb 8D5, which recognizes the N-terminal region of the PrP molecule. Using the PrP(Sc)-specific double immunostaining,...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Tanaka, Misaki, Fujiwara, Ai, Suzuki, Akio, Yamasaki, Takeshi, Hasebe, Rie, Masujin, Kentaro, Horiuchi, Motohiro
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770843/
https://ncbi.nlm.nih.gov/pubmed/27267758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000514
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