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Retrograde Transport by Clathrin-Coated Vesicles is Involved in Intracellular Transport of PrP(Sc) in Persistently Prion-Infected Cells

Intracellular dynamics of an abnormal isoform of prion protein (PrP(Sc)) are tightly associated with prion propagation. However, the machineries involved in the intracellular trafficking of PrP(Sc) are not fully understood. Our previous study suggested that PrP(Sc) in persistently prion-infected cel...

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Pubblicato in:Sci Rep
Autori principali: Yamasaki, Takeshi, Suzuki, Akio, Hasebe, Rie, Horiuchi, Motohiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095914/
https://ncbi.nlm.nih.gov/pubmed/30115966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30775-1
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