Serine 392 phosphorylation modulates p53 mitochondrial translocation and transcription-independent apoptosis

The tumor suppressor p53 is a key regulator of apoptosis induced by various cellular stresses. p53 can induce apoptosis by two mechanisms. First, p53 acts as a transcription factor inducing and repressing pro-apoptotic and anti-apoptotic targets genes, respectively. Second, p53 is able to translocat...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Differ
Asıl Yazarlar: Castrogiovanni, Cédric, Waterschoot, Béranger, De Backer, Olivier, Dumont, Patrick
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2018
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729520/
https://ncbi.nlm.nih.gov/pubmed/28937686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.143
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller