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Decrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20
Following a genotoxic stress, the tumor suppressor p53 translocates to mitochondria to take part in direct induction of apoptosis, via interaction with BCL-2 family members such as BAK and BAX. We determined the kinetics of the mitochondrial translocation of p53 in HCT-116 and PA-1 cells exposed to...
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| Publicado en: | Cancer Biol Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623441/ https://ncbi.nlm.nih.gov/pubmed/26252178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1070978 |
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