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Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice

Inflammation is a common denominator in chronic diseases of aging. Yet, how inflammation fuels these diseases remains unknown. Neutrophils are the primary leukocytes involved in the early phase of innate immunity and inflammation. As part of their anti-microbial defense, neutrophils form extracellul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Hayashi, Hideki, Cherpokova, Deya, Martinod, Kimberly, Witsch, Thilo, Wong, Siu Ling, Gallant, Maureen, Cifuni, Stephen M., Guarente, Leonard P., Wagner, Denisa D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728566/
https://ncbi.nlm.nih.gov/pubmed/29236713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188341
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