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Diabetes primes neutrophils to undergo NETosis which severely impairs wound healing

Wound healing is impaired in diabetes resulting in significant morbidity and mortality. Neutrophils are the main leukocytes involved in the early phase of healing. As part of their anti-microbial defense, neutrophils form extracellular traps (NETs) by releasing decondensed chromatin lined with cytot...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Wong, Siu Ling, Demers, Melanie, Martinod, Kimberly, Gallant, Maureen, Wang, Yanming, Goldfine, Allison B., Kahn, C. Ronald, Wagner, Denisa D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631120/
https://ncbi.nlm.nih.gov/pubmed/26076037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3887
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