Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice

Inflammation is a common denominator in chronic diseases of aging. Yet, how inflammation fuels these diseases remains unknown. Neutrophils are the primary leukocytes involved in the early phase of innate immunity and inflammation. As part of their anti-microbial defense, neutrophils form extracellul...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Hayashi, Hideki, Cherpokova, Deya, Martinod, Kimberly, Witsch, Thilo, Wong, Siu Ling, Gallant, Maureen, Cifuni, Stephen M., Guarente, Leonard P., Wagner, Denisa D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728566/
https://ncbi.nlm.nih.gov/pubmed/29236713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188341
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