Llwytho...

Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis

BACKGROUND: Neutrophil serine proteases have been implicated in coagulation and neutrophil extracellular trap (NET) formation. In human neutrophils, neutrophil elastase (NE) translocates to the nucleus during NETosis and cleaves histones, thus aiding in chromatin decondensation. NE(−/−) mice were sh...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Thromb Haemost
Prif Awduron: Martinod, Kimberly, Witsch, Thilo, Farley, Kalamo, Gallant, Maureen, Remold-O’Donnell, Eileen, Wagner, Denisa D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785059/
https://ncbi.nlm.nih.gov/pubmed/26712312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13239
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