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Neutrophil elastase-deficient mice form neutrophil extracellular traps in an experimental model of deep vein thrombosis
BACKGROUND: Neutrophil serine proteases have been implicated in coagulation and neutrophil extracellular trap (NET) formation. In human neutrophils, neutrophil elastase (NE) translocates to the nucleus during NETosis and cleaves histones, thus aiding in chromatin decondensation. NE(−/−) mice were sh...
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| Publicado en: | J Thromb Haemost |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4785059/ https://ncbi.nlm.nih.gov/pubmed/26712312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13239 |
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