Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

Cancer-associated thrombosis often lacks a clear etiology. However, it is linked to a poor prognosis and represents the second-leading cause of death in cancer patients. Recent studies have shown that chromatin released into blood, through the generation of neutrophil extracellular traps (NETs), is...

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Bibliographic Details
Main Authors: Demers, Mélanie, Krause, Daniela S., Schatzberg, Daphne, Martinod, Kimberly, Voorhees, Jaymie R., Fuchs, Tobias A., Scadden, David T., Wagner, Denisa D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420209/
https://ncbi.nlm.nih.gov/pubmed/22826226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200419109
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