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Co-occurrence of FLT3-TKD and NPM1 mutations defines a highly favorable prognostic AML group
Although FLT3 internal tandem duplication (ITD) mutations in acute myeloid leukemia (AML) confer an adverse prognosis, co-occurrence with a nucleophosphomin (NPM1) mutation partially improves response and survival outcomes. In contrast, simultaneous NPM1 and FLT3 tyrosine kinase domain (TKD) mutatio...
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| Publicat a: | Blood Adv |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728474/ https://ncbi.nlm.nih.gov/pubmed/29296796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009019 |
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