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Outcomes of older patients with NPM1-mutated AML: current treatments and the promise of venetoclax-based regimens
Nucleophosmin-1 mutations (NPM1(+)) occur in ∼30% of acute myeloid leukemia (AML) patients. Although typically associated with favorable prognosis, the beneficial impact of NPM1(+) decreases with increasing age in patients treated with standard intensive chemotherapy (IC) or hypomethylating agents (...
שמור ב:
| הוצא לאור ב: | Blood Adv |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7160266/ https://ncbi.nlm.nih.gov/pubmed/32251497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001267 |
| תגים: |
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