Mutated Nucleophosmin-1 (NPM1) in patients with Acute Myeloid Leukemia (AML) in remission and relapse

Patients with newly diagnosed AML (n=360) including 137 (38%) with normal karyotype (NK) were evaluated. Overall, 60 (16.6%) patients including 46 of the 137 (33.5%) NK patients had NPM1 mutation at baseline. Thirty nine patients (30 NK) had available NPM1 status at the time of CR and all (100%) wer...

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Hauptverfasser: Jain, Preetesh, Kantarjian, Hagop, Patel, Keyur, Faderl, Stefan, Garcia-Manero, Guillermo, Benjamini, Ohad, Borthakur, Gautam, Pemmaraju, Naveen, Kadia, Tapan, Daver, Naval, Nazha, Aziz, Luthra, Raja, Pierce, Sherry, Cortes, Jorge, Ravandi, Farhad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143910/
https://ncbi.nlm.nih.gov/pubmed/24004182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2013.840776
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