Biological and Clinical Features of Trisomy 21 in Adult Patients with Acute Myeloid Leukemia

INTRODUCTION: Trisomy 21 (+21) is frequently noted in patients with acute myeloid leukemia (AML). In adults, +21 has traditionally been considered an intermediate-risk cytogenetic aberration. METHODS: We analyzed 90 patients with newly diagnosed AML harboring +21. Four cytogenetic subgroups were def...

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Main Authors: Strati, Paolo, Daver, Naval, Ravandi, Farhad, Pemmaraju, Naveen, Pierce, Sherry, Garcia-Manero, Guillermo, Nazha, Aziz, Kadia, Tapan, Jabbour, Elias, Borthakur, Gautam, Faderl, Stefan, Quintas-Cardama, Alfonso, Kantarjian, Hagop, Cortes, Jorge
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101888/
https://ncbi.nlm.nih.gov/pubmed/23969309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2013.05.020
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