Effect of NPM1 and FLT3 Mutations on the Outcomes of Elderly Patients With Acute Myeloid Leukemia Receiving Standard Chemotherapy

This study analyzes the clinical impact of NPM1 and FLT3 mutations in AML patients 65 years of age or older treated with cytotoxic chemotherapy at our institution. A total of 557 patients were retrospectively reviewed. No difference in survivalwasnoted for patients with isolated FLT3 orNPM1mutations...

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Autores principales: Daver, Naval, Liu Dumlao, Theresa, Ravandi, Farhad, Pierce, Sherry, Borthakur, Gautam, Pemmaraju, Naveen, Nazha, Aziz, Faderl, Stefan, Jabbour, Elias, Garcia-Manero, Guillermo, Cortes, Jorges, Kantarjian, Hagop, Quintás-Cardama, Alfonso
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114766/
https://ncbi.nlm.nih.gov/pubmed/23763915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2013.02.021
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