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Prognostic implications of chromosome 17 abnormalities in the context of monosomal karyotype in patients with acute myeloid leukemia and complex cytogenetics

BACKGROUND: Chromosome 17 abnormalities (C17 abns) are associated with poor outcome in leukemias including acute myeloid leukemia (AML). Recently, Monosomal karyotype (MK) was introduced as independent predictor of dismal outcome in AML. The additional prognostic impact of C-17 abns in patients with...

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Detalhes bibliográficos
Main Authors: Nazha, Aziz, Kantarjian, Hagop M., Bhatt, Vijaya R., Nogueras-Gonzalez, Graciela, Cortes, Jorge E, Kadia, Tapan, Garcia-Manero, Guillermo, Abruzzo, Lynne, Daver, Naval, Pemmaraju, Naveen, Quintas-Cardama, Alfonso, Ravandi, Farhad, Keating, Michael, Borthakur, Gautam
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167660/
https://ncbi.nlm.nih.gov/pubmed/24461514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2013.07.009
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