Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways

B-1 and B-2 lymphocytes are derived from distinct developmental pathways and represent layered arms of the innate and adaptive immune systems, respectively. In contrast to a majority of murine B-cell malignancies, which stain positive with the B220 antibody, we discovered a novel form of B-cell leuk...

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Udgivet i:Blood Adv
Main Authors: Gough, Sheryl M., Goldberg, Liat, Pineda, Marbin, Walker, Robert L., Zhu, Yuelin J., Bilke, Sven, Chung, Yang Jo, Dufraine, Joseph, Kundu, Subhadip, Jacoby, Elad, Fry, Terry J., Fischer, Susanna, Panzer-Grümayer, Renate, Meltzer, Paul S., Aplan, Peter D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728343/
https://ncbi.nlm.nih.gov/pubmed/29296821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009837
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