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Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia
Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagnostic, prognostic markers and therapeutic targets. However, predicting the functional effect of these genetic alterations beyond affected genes and their...
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Опубликовано в: : | Mol Biol Cell |
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Главные авторы: | , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
The American Society for Cell Biology
2014
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244205/ https://ncbi.nlm.nih.gov/pubmed/25273558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1038 |
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