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Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia

Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagnostic, prognostic markers and therapeutic targets. However, predicting the functional effect of these genetic alterations beyond affected genes and their...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Hajingabo, Leon Juvenal, Daakour, Sarah, Martin, Maud, Grausenburger, Reinhard, Panzer-Grümayer, Renate, Dequiedt, Franck, Simonis, Nicolas, Twizere, Jean-Claude
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244205/
https://ncbi.nlm.nih.gov/pubmed/25273558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1038
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