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Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia

Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagnostic, prognostic markers and therapeutic targets. However, predicting the functional effect of these genetic alterations beyond affected genes and their...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Hajingabo, Leon Juvenal, Daakour, Sarah, Martin, Maud, Grausenburger, Reinhard, Panzer-Grümayer, Renate, Dequiedt, Franck, Simonis, Nicolas, Twizere, Jean-Claude
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244205/
https://ncbi.nlm.nih.gov/pubmed/25273558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1038
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