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Predicting interactome network perturbations in human cancer: application to gene fusions in acute lymphoblastic leukemia

Genomic variations such as point mutations and gene fusions are directly or indirectly associated with human diseases. They are recognized as diagnostic, prognostic markers and therapeutic targets. However, predicting the functional effect of these genetic alterations beyond affected genes and their...

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Hajingabo, Leon Juvenal, Daakour, Sarah, Martin, Maud, Grausenburger, Reinhard, Panzer-Grümayer, Renate, Dequiedt, Franck, Simonis, Nicolas, Twizere, Jean-Claude
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244205/
https://ncbi.nlm.nih.gov/pubmed/25273558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1038
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