CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia

Despite their apparently good prognosis ~15% of high hyperdiploid (HD) childhood acute lymphoblastic leukemia (ALL) cases relapse. To search for responsible risk factors we determined copy number aberrations as well as copy neutral loss of heterozygosity (LOH) in 13 matched diagnosis and relapse sam...

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Main Authors: Inthal, A, Zeitlhofer, P, Zeginigg, M, Morak, M, Grausenburger, R, Fronkova, E, Fahrner, B, Mann, G, Haas, OA, Panzer-Grümayer, R
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194312/
https://ncbi.nlm.nih.gov/pubmed/22388726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.60
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