HSC extrinsic sex-related and intrinsic autoimmune disease–related human B-cell variation is recapitulated in humanized mice

B cells play a major role in antigen presentation and antibody production in the development of autoimmune diseases, and some of these diseases disproportionally occur in females. Moreover, immune responses tend to be stronger in female vs male humans and mice. Because it is challenging to distingui...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Borsotti, Chiara, Danzl, Nichole M., Nauman, Grace, Hölzl, Markus A., French, Clare, Chavez, Estefania, Khosravi-Maharlooei, Mohsen, Glauzy, Salome, Delmotte, Fabien R., Meffre, Eric, Savage, David G., Campbell, Sean R., Goland, Robin, Greenberg, Ellen, Bi, Jing, Satwani, Prakash, Yang, Suxiao, Bathon, Joan, Winchester, Robert, Sykes, Megan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2017
Gaiak:
Immunobiology and Immunotherapy
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728279/
https://ncbi.nlm.nih.gov/pubmed/29296847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006932
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