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Reduced positive selection of a human TCR in a swine thymus using a humanized mouse model for xenotolerance induction

Tolerance-inducing approaches to xenotransplantation would be optimal and may be necessary for long-term survival of transplanted pig organs in human patients. The ideal approach would generate donor-specific unresponsiveness to the pig organ without suppressing the patient’s normal immune function....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Xenotransplantation
Egile Nagusiak: Nauman, Grace, Borsotti, Chiara, Danzl, Nichole, Khosravi-Maharlooei, Mohsen, Li, Hao-Wei, Chavez, Estefania, Stone, Samantha, Sykes, Megan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007369/
https://ncbi.nlm.nih.gov/pubmed/31565822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12558
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