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Reduced positive selection of a human TCR in a swine thymus using a humanized mouse model for xenotolerance induction
Tolerance-inducing approaches to xenotransplantation would be optimal and may be necessary for long-term survival of transplanted pig organs in human patients. The ideal approach would generate donor-specific unresponsiveness to the pig organ without suppressing the patient’s normal immune function....
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| Publicado en: | Xenotransplantation |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007369/ https://ncbi.nlm.nih.gov/pubmed/31565822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12558 |
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