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Type 1 diabetes induction in humanized mice

There is an urgent and unmet need for humanized in vivo models of type 1 diabetes to study immunopathogenesis and immunotherapy, and in particular antigen-specific therapy. Transfer of patient blood lymphocytes to immunodeficient mice is associated with xenogeneic graft-versus-host reactivity that c...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Tan, Shulian, Li, Yang, Xia, Jinxing, Jin, Chun-Hui, Hu, Zheng, Duinkerken, Gaby, Li, Yuying, Khosravi Maharlooei, Mohsen, Chavez, Estefania, Nauman, Grace, Danzl, Nichole, Nakayama, Maki, Roep, Bart O., Sykes, Megan, Yang, Yong-Guang
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642714/
https://ncbi.nlm.nih.gov/pubmed/28874533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710415114
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