Type 1 diabetes induction in humanized mice

There is an urgent and unmet need for humanized in vivo models of type 1 diabetes to study immunopathogenesis and immunotherapy, and in particular antigen-specific therapy. Transfer of patient blood lymphocytes to immunodeficient mice is associated with xenogeneic graft-versus-host reactivity that c...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tan, Shulian, Li, Yang, Xia, Jinxing, Jin, Chun-Hui, Hu, Zheng, Duinkerken, Gaby, Li, Yuying, Khosravi Maharlooei, Mohsen, Chavez, Estefania, Nauman, Grace, Danzl, Nichole, Nakayama, Maki, Roep, Bart O., Sykes, Megan, Yang, Yong-Guang
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642714/
https://ncbi.nlm.nih.gov/pubmed/28874533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710415114
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items