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Bulky Lesion Bypass Requires Dpo4 Binding in Distinct Conformations
Translesion DNA synthesis is an essential process that helps resume DNA replication at forks stalled near bulky adducts on the DNA. Benzo[a]pyrene (B[a]P) is a polycyclic aromatic hydrocarbon (PAH) that can be metabolically activated to benzo[a]pyrene diol epoxide (BPDE), which then can react with D...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727293/ https://ncbi.nlm.nih.gov/pubmed/29234107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17643-0 |
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