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Nucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment
Y-family DNA polymerases play a crucial role in translesion DNA synthesis. Here, we have characterized the binding kinetics and conformational dynamics of the Y-family polymerase Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) using single-molecule fluorescence. We find that in the absence of dN...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936744/ https://ncbi.nlm.nih.gov/pubmed/24270793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1149 |
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