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Mechanism of aromatic amine carcinogen bypass by the Y-family polymerase, Dpo4
Bulky DNA damage inhibits DNA synthesis by replicative polymerases and often requires the action of error prone bypass polymerases. The exact mechanism governing adduct-induced mutagenesis and its dependence on the DNA sequence context remains unclear. In this work, we characterize Dpo4 binding conf...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4787768/ https://ncbi.nlm.nih.gov/pubmed/26481355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1067 |
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