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Endogenous and agonist-induced opening of mitochondrial big vs. small Ca(2+)-sensitive K(+) channels on cardiac cell and mitochondrial protection

Both big (BK(Ca)) and small (SK(Ca)) conductance Ca(2+)-sensitive K(+) channels are present in mammalian cardiac cell mitochondria (m). We used pharmacological agonists and antagonists of BK(Ca) and SK(Ca) channels to examine the importance of endogenous opening of these channels and the relative co...

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Dades bibliogràfiques
Publicat a:J Cardiovasc Pharmacol
Autors principals: Stowe, David F., Yang, Meiying, Heisner, James S., Camara, Amadou K.S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726766/
https://ncbi.nlm.nih.gov/pubmed/28777255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000524
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