Llwytho...
Ranolazine reduces Ca(2+) overload and oxidative stress and improves mitochondrial integrity to protect against ischemia reperfusion injury in isolated hearts
Ranolazine is a clinically approved drug for treating cardiac ventricular dysrhythmias and angina. Its mechanism(s) of protection is not clearly understood but evidence points to blocking the late Na(+) current that arises during ischemia, blocking mitochondrial complex I activity, or modulating mit...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2011
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233383/ https://ncbi.nlm.nih.gov/pubmed/21741479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2011.06.018 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|