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Reduced mitochondrial Ca(2+) loading and improved functional recovery after ischemia-reperfusion injury in old vs. young guinea pig hearts
Oxidative damage and impaired cytosolic Ca(2+) concentration ([Ca(2+)](cyto)) handling are associated with mitochondrial [Ca(2+)] ([Ca(2+)](mito)) overload and depressed functional recovery after cardiac ischemia-reperfusion (I/R) injury. We hypothesized that hearts from old guinea pigs would demons...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353793/ https://ncbi.nlm.nih.gov/pubmed/22140052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00533.2011 |
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