Reduced mitochondrial Ca(2+) loading and improved functional recovery after ischemia-reperfusion injury in old vs. young guinea pig hearts

Oxidative damage and impaired cytosolic Ca(2+) concentration ([Ca(2+)](cyto)) handling are associated with mitochondrial [Ca(2+)] ([Ca(2+)](mito)) overload and depressed functional recovery after cardiac ischemia-reperfusion (I/R) injury. We hypothesized that hearts from old guinea pigs would demons...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rhodes, Samhita S., Camara, Amadou K. S., Heisner, James S., Riess, Matthias L., Aldakkak, Mohammed, Stowe, David F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Integrative Cardiovascular Physiology and Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353793/
https://ncbi.nlm.nih.gov/pubmed/22140052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00533.2011
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge