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Endogenous and agonist-induced opening of mitochondrial big vs. small Ca(2+)-sensitive K(+) channels on cardiac cell and mitochondrial protection

Both big (BK(Ca)) and small (SK(Ca)) conductance Ca(2+)-sensitive K(+) channels are present in mammalian cardiac cell mitochondria (m). We used pharmacological agonists and antagonists of BK(Ca) and SK(Ca) channels to examine the importance of endogenous opening of these channels and the relative co...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Stowe, David F., Yang, Meiying, Heisner, James S., Camara, Amadou K.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726766/
https://ncbi.nlm.nih.gov/pubmed/28777255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000524
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