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Modulation of peroxynitrite produced via mitochondrial nitric oxide synthesis during Ca(2+) and succinate-induced oxidative stress in cardiac isolated mitochondria
We hypothesized that NO(•) is generated in isolated cardiac mitochondria as the source for ONOO(−) production during oxidative stress. We monitored generation of ONOO(−) from guinea pig isolated cardiac mitochondria subjected to excess Ca(2+) uptake before adding succinate and determined if ONOO(−)...
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| Publicado no: | Biochim Biophys Acta Bioenerg |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7560995/ https://ncbi.nlm.nih.gov/pubmed/32828729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2020.148290 |
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