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Protection against cardiac injury by small Ca(2+)-sensitive K(+) channels identified in guinea pig cardiac inner mitochondrial membrane

We tested if small conductance, Ca(2+)-sensitive K(+) channels (SK(Ca)) precondition hearts against ischemia reperfusion (IR) injury by improving mitochondrial (m) bioenergetics, if O(2)–derived free radicals are required to initiate protection via SK(Ca) channels, and, importantly, if SK(Ca) channe...

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Detalhes bibliográficos
Main Authors: Stowe, David F., Gadicherla, Ashish K., Zhou, Yifan, Aldakkak, Mohammed, Cheng, Qunli, Kwok, Wai-Meng, Jiang, Ming Tao, Heisner, James S., Yang, Mei Ying, Camara, Amadou K.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534888/
https://ncbi.nlm.nih.gov/pubmed/22982251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.08.031
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