Protection against cardiac injury by small Ca(2+)-sensitive K(+) channels identified in guinea pig cardiac inner mitochondrial membrane

We tested if small conductance, Ca(2+)-sensitive K(+) channels (SK(Ca)) precondition hearts against ischemia reperfusion (IR) injury by improving mitochondrial (m) bioenergetics, if O(2)–derived free radicals are required to initiate protection via SK(Ca) channels, and, importantly, if SK(Ca) channe...

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Hauptverfasser: Stowe, David F., Gadicherla, Ashish K., Zhou, Yifan, Aldakkak, Mohammed, Cheng, Qunli, Kwok, Wai-Meng, Jiang, Ming Tao, Heisner, James S., Yang, Mei Ying, Camara, Amadou K.S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534888/
https://ncbi.nlm.nih.gov/pubmed/22982251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.08.031
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