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Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion

BACKGROUND: Despite effectiveness of the combined antiretroviral therapy, HIV-1 persists in long-lived latently infected cells. Consequently, new therapeutic approaches aimed at eliminating this latent reservoir are currently being developed. A “shock and kill” strategy using latency-reversing agent...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Proust, Alizé, Barat, Corinne, Leboeuf, Mathieu, Drouin, Jean, Tremblay, Michel J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725742/
https://ncbi.nlm.nih.gov/pubmed/29228979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1019-y
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