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The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1

A potential strategy to cure HIV-1 infection is to use latency reversing agents (LRAs) to eliminate latent reservoirs established in resting CD4+ T (rCD4+) cells. As no drug has been shown to be completely effective, finding new drugs and combinations are of increasing importance. We studied the eff...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: López-Huertas, María Rosa, Jiménez-Tormo, Laura, Madrid-Elena, Nadia, Gutiérrez, Carolina, Rodríguez-Mora, Sara, Coiras, Mayte, Alcamí, José, Moreno, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443841/
https://ncbi.nlm.nih.gov/pubmed/28539614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02634-y
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