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Epigenetic Regulation of HIV-1 Latency in Astrocytes

HIV infiltrates the brain at early times postinfection and remains latent within astrocytes and macrophages. Because astrocytes are the most abundant cell type in the brain, we evaluated epigenetic regulation of HIV latency in astrocytes. We have shown that class I histone deacetylases (HDACs) and a...

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Bibliografiske detaljer
Main Authors: Narasipura, Srinivas D., Kim, Stephanie, Al-Harthi, Lena
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958059/
https://ncbi.nlm.nih.gov/pubmed/24352441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03333-13
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