Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration

Integrin αβ heterodimer cell surface receptors mediate adhesive interactions that provide traction for cell migration. Here, we test whether the integrin, when engaged to an extracellular ligand and the cytoskeleton, adopts a specific orientation dictated by the direction of actin flow on the surfac...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Nordenfelt, Pontus, Moore, Travis I., Mehta, Shalin B., Kalappurakkal, Joseph Mathew, Swaminathan, Vinay, Koga, Nobuyasu, Lambert, Talley J., Baker, David, Waters, Jennifer C., Oldenbourg, Rudolf, Tani, Tomomi, Mayor, Satyajit, Waterman, Clare M., Springer, Timothy A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725580/
https://ncbi.nlm.nih.gov/pubmed/29229906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01848-y
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki