Common SAR Derived from Linear and Non-linear QSAR Studies on AChE Inhibitors used in the Treatment of Alzheimer’s Disease

BACKGROUND: Deficits in cholinergic neurotransmission due to the degeneration of cholinergic neurons in the brain are believed to be one of the major causes of the memory impairments associated with AD. Targeting acetyl cholinesterase (AChE) surfaced as a potential therapeutic target in the treatmen...

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Veröffentlicht in:Curr Neuropharmacol
Hauptverfasser: Pulikkal, Babitha Pallikkara, Marunnan, Sahila Mohammed, Bandaru, Srinivas, Yadav, Mukesh, Nayarisseri, Anuraj, Sureshkumar, Sivanpillai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725541/
https://ncbi.nlm.nih.gov/pubmed/27964704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X14666161213142841
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