Structural basis for the in vitro known acyl-depsipeptide 2 (ADEP2) inhibition to Clp 2 protease from Mycobacterium tuberculosis

Inhibition of Mycobacterium tuberculosis Clp 2 protease has emerged as an attractive therapeutic option for treatment. Acyldepsipeptides (ADEPs) is known as an inhibitor for Clp 2 protease. Therefore, it is of interest to document its affinity, enzyme activity and ADME profiles. We report the predic...

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Foilsithe in:Bioinformation
Main Authors: Khandekar, Natasha, Singh, Snehal, Shukla, Ruchi, Tirumalaraju, Sridevi, Bandaru, Srinivas, Banerjee, Tushar, Nayarisseri, Anuraj
Formáid: Artigo
Teanga:Inglês
Foilsithe: Biomedical Informatics 2016
Ábhair:
Hypothesis
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267950/
https://ncbi.nlm.nih.gov/pubmed/28149041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630012092
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