Molecular docking approaches in identification of High affinity inhibitors of Human SMO receptor

Inappropriate activation of the Hh signaling pathway has been implicated in the development of several types of cancers including prostate, lung, pancreas, breast, brain and skin. Present study identified the binding affinities of eight established inhibitors viz., Cyclopamine, Saridegib, Itraconazo...

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Bibliographic Details
Published in:Bioinformation
Main Authors: Akare, Uday Raj, Bandaru, Srinivas, Shaheen, Uzma, Singh, Pramod Kumar, Tiwari, Geet, Singare, Paramanand, Nayarisseri, Anuraj, Banerjee, Tushar
Format: Artigo
Language:Inglês
Published: Biomedical Informatics 2014
Subjects:
Hypothesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312366/
https://ncbi.nlm.nih.gov/pubmed/25670876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010737
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