Molecular docking approaches in identification of High affinity inhibitors of Human SMO receptor

Inappropriate activation of the Hh signaling pathway has been implicated in the development of several types of cancers including prostate, lung, pancreas, breast, brain and skin. Present study identified the binding affinities of eight established inhibitors viz., Cyclopamine, Saridegib, Itraconazo...

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Dades bibliogràfiques
Publicat a:Bioinformation
Autors principals: Akare, Uday Raj, Bandaru, Srinivas, Shaheen, Uzma, Singh, Pramod Kumar, Tiwari, Geet, Singare, Paramanand, Nayarisseri, Anuraj, Banerjee, Tushar
Format: Artigo
Idioma:Inglês
Publicat: Biomedical Informatics 2014
Matèries:
Hypothesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312366/
https://ncbi.nlm.nih.gov/pubmed/25670876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010737
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