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Molecular docking approaches in identification of High affinity inhibitors of Human SMO receptor

Inappropriate activation of the Hh signaling pathway has been implicated in the development of several types of cancers including prostate, lung, pancreas, breast, brain and skin. Present study identified the binding affinities of eight established inhibitors viz., Cyclopamine, Saridegib, Itraconazo...

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Detalhes bibliográficos
Publicado no:Bioinformation
Main Authors: Akare, Uday Raj, Bandaru, Srinivas, Shaheen, Uzma, Singh, Pramod Kumar, Tiwari, Geet, Singare, Paramanand, Nayarisseri, Anuraj, Banerjee, Tushar
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312366/
https://ncbi.nlm.nih.gov/pubmed/25670876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010737
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