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Common SAR Derived from Linear and Non-linear QSAR Studies on AChE Inhibitors used in the Treatment of Alzheimer’s Disease

BACKGROUND: Deficits in cholinergic neurotransmission due to the degeneration of cholinergic neurons in the brain are believed to be one of the major causes of the memory impairments associated with AD. Targeting acetyl cholinesterase (AChE) surfaced as a potential therapeutic target in the treatmen...

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Podrobná bibliografie
Vydáno v:Curr Neuropharmacol
Hlavní autoři: Pulikkal, Babitha Pallikkara, Marunnan, Sahila Mohammed, Bandaru, Srinivas, Yadav, Mukesh, Nayarisseri, Anuraj, Sureshkumar, Sivanpillai
Médium: Artigo
Jazyk:Inglês
Vydáno: Bentham Science Publishers 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725541/
https://ncbi.nlm.nih.gov/pubmed/27964704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X14666161213142841
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