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Common SAR Derived from Linear and Non-linear QSAR Studies on AChE Inhibitors used in the Treatment of Alzheimer’s Disease

BACKGROUND: Deficits in cholinergic neurotransmission due to the degeneration of cholinergic neurons in the brain are believed to be one of the major causes of the memory impairments associated with AD. Targeting acetyl cholinesterase (AChE) surfaced as a potential therapeutic target in the treatmen...

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Detalhes bibliográficos
Publicado no:Curr Neuropharmacol
Main Authors: Pulikkal, Babitha Pallikkara, Marunnan, Sahila Mohammed, Bandaru, Srinivas, Yadav, Mukesh, Nayarisseri, Anuraj, Sureshkumar, Sivanpillai
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725541/
https://ncbi.nlm.nih.gov/pubmed/27964704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X14666161213142841
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