Development of MLR and SVM Aided QSAR Models to Identify Common SAR of GABA Uptake Herbal Inhibitors used in the Treatment of Schizophrenia

BACKGROUND: Alterations in GABAnergic system are implicated in the pathophysiology of schizophrenia. Available antipsychotics that target GABA receptor form a desirable therapeutic strategy in the treatment regimen of schizophrenia, unfortunately, suffer serious setback due to their prolonged side e...

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Publicado no:Curr Neuropharmacol
Main Authors: Marunnan, Sahila Mohammed, Pulikkal, Babitha Pallikkara, Jabamalairaj, Anitha, Bandaru, Srinivas, Yadav, Mukesh, Nayarisseri, Anuraj, Doss, Victor Arokia
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725540/
https://ncbi.nlm.nih.gov/pubmed/27919211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1567201814666161205131745
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