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Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis

Spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are severe nervous system diseases characterized by the degeneration of lower motor neurons. They share a number of additional pathological, cellular, and genetic parallels suggesting that mechanistic and clinical insights into on...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Tosolini, Andrew P., Sleigh, James N.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725447/
https://ncbi.nlm.nih.gov/pubmed/29270111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00405
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